Towards cultivar-oriented gene discovery for better crops

The continued expansion of the world population, increasingly inconsistent climate and shrinking agricultural resources present major challenges to crop breeding. Fortunately, the increasing ability to discover and manipulate genes creates new opportunities to develop more productive and resilient cultivars. Many genes have been described in papers as being beneficial for yield increase. However, few of them have been translated into increased yield on farms. In contrast, commercial breeders are facing gene decidophobia, i.e., puzzled about which gene to choose for breeding among the many identified, a huge chasm between gene discovery and cultivar innovation. The purpose of this paper is to draw attention to the shortfalls in current gene discovery research and to emphasise the need to align with cultivar innovation. The methodology dictates that genetic studies not only focus on gene discovery but also pay good attention to the genetic backgrounds, experimental validation in relevant environments, appropriate crop management, and data reusability. The close of the gaps should accelerate the application of molecular study in breeding and contribute to future global food security.

Cultivar innovation;Data reusability;Gene discovery;Gene decidophobia;Omnigenic model